Ocular Complications of Infantile Nephropathic Cystinosis.

Ocular complications are among the most common cause of discomfort and disability in patients with cystinosis, affecting virtually all individuals with nephropathic cystinosis if left untreated. Photophobia results from accumulation of cystine crystals within the corneal tissue. Compliance with recommended therapy can reverse this change, resulting in resolution of symptoms. Other ocular structures also suffer from cystine accumulation, and early and diligent systemic and local treatment prevents the most severe, irreversible, complications including vision loss.